Publications in the last 5 years:

Names of corresponding authors are bolded and names of my MSc students are underlined.  Names of my undergraduate students are underlined and italicized.

Names of my research assistants and research associate are underlined and marked with asterisk.

 2010:

1.      Kim S-E, Gorrell A, Rader S, Lee CH. (2010) Endoribonuclease activity of human APE1 revealed by a real-time fluorometric assay. Anal Biochem 398: 69-75.

2.      Tell G, Wilson DM III, Lee CH. (2010) Intrusion of a DNA-repair protein in the RNome world: is this a beginning of a new era?  Mol Cell Biol 30: 366-371.

3.      Li W-M*, Barnes T, Lee CH. (2010) Endoribonucleases: enzymes gaining spotlight in mRNA metabolism.  FEBS J 277: 627-641.

4.   Kim W-C, King D, Lee CH. (2010) RNA-cleaving properties of human apurinic/apyrimidinic endonuclease1 (APE1). Int J Biochem Mol Biol 1: 12-25.

5.   Lee CH. (2010) Reversing agents for ATP-binding cassette drug transporters. Methods Mol Biol 596: 325-340.

2009:

1.     Barnes T, Kim W-C, Mantha A, Kim S-E, Izumi T, Sankar M, Lee CH.  (2009) Identification of apurinic/apyrimidinic endonuclease APE1 as the endoribonuclease that cleaves c-myc mRNA.  Nucleic Acids Res. 37: 3946-3958.

2.    Kim W-C, Lee CH. (2009) The role of mammalian ribonucleases (RNases) in cancer.  Biochim Biophys Acta-Reviews on Cancer 1796: 99-113.

2008:

1.       Bassett T, Harpur B, Kuo HK, Lee CH. (2008) Effective stimulation of growth in MCF-7 human breast cancer cells by inhibition of syntaxin18 by external guide sequence and ribonuclease P.  Cancer Letts 272:167-175.

2007:

1.    Tafech A, Bennett W, Mills F, Lee CH. (2007) Identification of c-myc coding region determinant RNA sequences and structures cleaved by an RNase1-like endoribonuclease.  Biochim Biophys Acta 1769: 49-60.

2.    Sparanese D, Lee CH.  (2007) CRD-BP shields c-myc and MDR-1 RNA from endonucleolytic attack by a mammalian endoribonuclease.  Nucleic Acids Res 35: 1209-1221.

2006:

1.    Tafech A, Bassett T, Sparanese D, Lee CH.  (2006) Destroying RNA as a Therapeutic Approach.  Curr Med Chem 13: 863-881.

2.    Bergstrom K*, Urquhart J, Tafech A, Doyle E, Lee CH.  (2006) Purification and characterization of a novel mammalian endoribonuclease.  J Cell Biochem 98: 519-537.

2005:

1.    Lee CH, Rehaume V*, Shandro J. (2005) Identification of in vivo P-glycoprotein mRNA decay intermediates in normal liver but not in liver tumors.  J Cell Physiol  204: 638-645.

2004:

1.    Eberding A, Rehaume V*, Lee CH. (2004) Detection of mRNA degradation intermediates in tissues using 3'end poly(A)-tailing polymerase chain reaction method.  Anal Biochem 335: 58-65.

2.    Lee CH. (2004) Drug resistance in cancer therapy: Reversing agents for ABC drug transporters. Curr Med Chem Anti-Cancer Agents 4: 1-10.