GUY PLOURDE

Associate Professor

Ph.D. University of Manitoba

Organic Chemistry


My research interests include: 

 (a)     asymmetric synthetic 
           methodology and its application to
           the synthesis of natural products; 

 (b)     isolation, characterization and 
           synthesis of natural 
           products found in medicinal 
           plants used by First 
           Nations of Northern British 
           Columbia; and 

 (c)     medicinal chemistry focusing on 
          anti-cancer active compounds. 

My most recent work involves a study of the diastereoselective spiroannulation of phenolic derivatives, (ref. 10 below).



Selected Articles

1)    Guy L. Plourde, ()-1-(4-Hydroxy-3-methoxyphenyl)-3-butanol,  Molbank 2003, M315.

2)    Guy L. Plourde, ()-7-Methoxy-2-methyl-1-oxaspiro[4,5]deca-6,9-diene-8-one,  Molbank 2003, M316.

3)    Guy L. Plourde, 1-(4-Hydroxy-3-methoxyphenyl)-4-methyl-3-pentanone, Molbank 2003, M317.

4)    Guy L. Plourde, ()-1-(4-Hydroxy-3-methoxyphenyl)-4-methyl-3-pentanol, Molbank 2003, M318.

5)    Guy L. Plourde, ()-7-Methoxy-2-ipropyl-1-oxaspiro[4,5]deca-6,9-diene-8-one, Molbank 2003, M319.

6)    Guy L. Plourde,1-(4-Hydroxy-3-methoxyphenyl)-4,4-dimethyl-3-pentanone, Molbank 2003, M320.

7)    Guy L. Plourde, ()-1-(4-Hydroxy-3-methoxyphenyl)-4,4-dimethyl-3-pentanol, Molbank 2003, M321.

8)    Guy L. Plourde, ()-2-tButyl-7-methoxy-1-oxaspiro[4,5]deca-6,9-diene-8-one, Molbank 2003, M322.

9)    Guy L. Plourde and Randy R. Spaetzel, Regioselective Protection of the 4-Hydroxyl of
3,4-Dihydroxybenaldehyde, Molecules, 2002, 7, 697-705.

10)    G.L. Plourde, Studies towards the diastereoselective spiroannulation of phenolic derivatives,
Tetrahedron Letters, 2002 (43) 3597-3599.

11)    G.L. Plourde and B.B. Fisher, Synthesis of 6-methoxy-1- oxaspiro[4,5] deca-6,9-diene-8-one, Molecules, 2002(7), 315-319.

12)    M.A. Bernards, W.D. Fleming, D.B. Llewellyn, R. Priefer, X. Yang, A. Sabatino, G.L. Plourde, Biochemical Characterization of the Suberization-Associated Anionic Peroxidase of Potato (Solanum tuberosum L.), Plant Physiology, 1999 (121), 135-145.

13)    G.L. Plourde, R. Priefer, D.B. Llewellyn, Synthesis and Characterization of 1-Hydroxy-2-methoxy-4-(3-propanoic acid) Anthracene, Synthetic Communications, 1999 (29), 2895-2901.

14)    E. Piers, N.L. Breau, Y. Han, G.L. Plourde, and W.-L. Yeh, 'Total Synthesis of cis Clerodane Diterpenoids: (-)Agelasin A and (+)-(3R,4S,5R,8S,9R,10S)-3,4-Epoxyclerod-13-en-15,16-olide.', J. Chem. Soc., Perkin Trans. I, 1995, 963.



 
 

Dr. Guy Plourde, Associate Professor
University of Northern British Columbia
Chemistry Program
3333 University Way
Prince George, B.C.
V2N 4Z9

Phone: (250) 960-6694
Fax: (250) 960-5845

or email:
(plourde@unbc.ca)
 


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